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Learn about Erectile Dysfunction and Sildenafil Citrate Online

Have you ever wondered how sildenafil acts within your body to help you solve your problems with erectile dysfunction?  Thanks to the instant availability of the Internet and computer devices, you will now be able to learn about ED and sildenafil citrate online right at your fingertips.

If you are curious as to how PDE5 inhibitors such as sildenafil work inside your body, then you can browse on search engines by simply typing in the search box the words sildenafil citrate online.  When you read about the mechanics of the action of sildenafil citrate online, you will learn that it helps protect the enzyme cGMP (short for cyclic guanosine monophosphate) from being degraded by the cGMP-specific PDE5 (short for phosphodiesterase type 5 enzyme) which are evidently located in the penile corpus cavernosum of men.  The free radical NO (short for nitric oxide) found in the penile corpus cavernosum adheres itself to what are called the guanylate cyclase receptors, which then results to the occurrence of elevated amounts of cGMP, thereby leading to the vasodilation or relaxation of the smooth muscles of the inner lining cushions of the helicine arteries (tendril-like arteries of the penis importantly involved in the process of its erection).  Once the smooth muscles relax, it will result to vasodilation and therefore there will be an increased supply of blood flowing into the penile spongy tissue, and the end result would be a successful penile erection.

Additionally, what you would also learn about sildenafil citrate online is that its special molecular makeup is somewhat similar to cGMP (located in the penile corpus cavernosum as well) and functions as an aggressive binding element of PDE5 in the penile corpus cavernosum, which results to more concentrations of cGMP and even better occurrences of erections. Avery important information that men will learn through reading about sildenafil citrate online is that sildenafil will be rendered useless without the introduction of one or more sexual stimuli, since only a sexual stimulus will be the only factor that can initiate the activation of the nitric oxide and cGMP inside a man’s body. Read more…

The 7 best medical smartphone apps

There’s revolution in the air, and it's called Wi-Fi. Wireless-internet-equipped smartphones like iPhones, BlackBerrys and Palms are more than just new variations on your trusty pager or your cell: smartphones are changing the way some physicians practice.

"Times have changed in the PDA world,” says Dr Paul Arnold, a Toronto emergency physician who used to edit the Medical Palm Review. The difference now? On-the-go internet access via Wi-Fi or 3G networking.

"It definitely has changed the way we do medicine," says Vancouver family medicine resident Jessica Otte. "I can get the information I need right away."

How are these plugged-in doctors using their smartphones in clinical settings to save time and improve patient care? Parkhurst Exchange spoke to clinicians from across Canada and overseas to find the best applications.

1. Epocrates. Without equal among mobile pharmacopeias, and by consensus the most useful app around, Epocrates provides detailed prescribing information at your fingertips. Even though it doesn’t list some Canadian formulations and is missing a few OTC drugs, it puts a library’s-worth of reliable, constantly updated drug information right in your pocket. (; all platforms; basic version free, expanded version US$159/year)

Click here to read the rest of this article on the Parkhurst Exchange website.

Image: Osirix

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  1. sharonNovember 10, 2009 at 10:49 AM

    Looking over some of the "Rx R US" ethic of Venture Capital partners ( e.g. Interwest with Epocrates)
    ........versus ..........
    a pure "research the illness" ethic ........
    we see a narrowing in the "scope" of the physician...
    .and a broadening in the "scale" of the pharmaceutical industry.

    These are not "diagnostic tools" at an investigative level .
    These are diagnostic and treatment tools at an informative level .

    The thrust is not discover. The thrust is apply.

    In the TMT executive mix I see there are economists at partnering levels ... a discipline who now have their own "blooming" season of "pop"ular economics as related to business in the paperback world.

    e.g The wisdom of Crowds by James Surowiecki

    paste of review

    If four basic conditions are met, a crowd's "collective intelligence" will produce better outcomes than a small group of experts, Surowiecki says, even if members of the crowd don't know all the facts or choose, individually, to act irrationally. "Wise crowds" need
    (1) diversity of opinion; brings in different information
    (2) independence of members from one another; keeps people from being swayed by a single opinion leader
    (3)decentralization; and
    (4)a good method for aggregating opinions.; people's errors balance each other out; and including all opinions guarantees that the results are "smarter" than if a single expert had been in charge.

    end of review
    ( hmmmmm...could a classroom be a crowd? could a smartphone app be the opposite?)

    Are these "apps" evidence of the broadening of the collective ownership" ( of seelcted information ) movement touted by economist David McMullen?:

    Bright Future: Abundance and Progress in the 21st Century (Paperback)

    excerpt of review:

    Bright Future offers three reasons for being positive about the 21st century:

    1. Human ingenuity and modest growth rates will bring affluence to most of the world by the end of the century.

    2. Environmental catastrophes will continue to not happen. Nature is remarkably resilient. And, as we get richer and smarter we will get better at remedying or adapting to natural adversity.

    3. A switch to collective ownership will become the obvious choice as automation eliminates most of the jobs that are not their own reward. Such a change would unleash the creative energies of the individual and free the economy from the distorting effects of sectional interests. This would be real free enterprise.

    end of review

    [+ note how " ingenuity" has replaced " innovation" as we have surrendered the hope for finding a new accepting creative input on fixing what we already have.

    +note how the environmental message may only be true because of the economic advantage of carbon trading

    + note the recognition of " a job not being it's own reward" and sectional interests being removed is now defined by who the "collaborators" are..... versus interdisciplinary alliances

    Don't you find this " settling"..... unsettling ? :( ]

    As for me I remain a fan of the broad and varied strength of the "learning" process.... not just the "teaching" linkage of a private goal with a ?public interest.

  2. drottematicNovember 12, 2009 at 2:43 AM

    Thanks for including me in this, Sam. It will be interesting to see how medical education and practice evolves in the context of our increasingly useful second (smartphone) brains.

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