Learn about Erectile Dysfunction and Sildenafil Citrate Online

Have you ever wondered how sildenafil acts within your body to help you solve your problems with erectile dysfunction?  Thanks to the instant availability of the Internet and computer devices, you will now be able to learn about ED and sildenafil citrate online right at your fingertips.

If you are curious as to how PDE5 inhibitors such as sildenafil work inside your body, then you can browse on search engines by simply typing in the search box the words sildenafil citrate online.  When you read about the mechanics of the action of sildenafil citrate online, you will learn that it helps protect the enzyme cGMP (short for cyclic guanosine monophosphate) from being degraded by the cGMP-specific PDE5 (short for phosphodiesterase type 5 enzyme) which are evidently located in the penile corpus cavernosum of men.  The free radical NO (short for nitric oxide) found in the penile corpus cavernosum adheres itself to what are called the guanylate cyclase receptors, which then results to the occurrence of elevated amounts of cGMP, thereby leading to the vasodilation or relaxation of the smooth muscles of the inner lining cushions of the helicine arteries (tendril-like arteries of the penis importantly involved in the process of its erection).  Once the smooth muscles relax, it will result to vasodilation and therefore there will be an increased supply of blood flowing into the penile spongy tissue, and the end result would be a successful penile erection.

Additionally, what you would also learn about sildenafil citrate online is that its special molecular makeup is somewhat similar to cGMP (located in the penile corpus cavernosum as well) and functions as an aggressive binding element of PDE5 in the penile corpus cavernosum, which results to more concentrations of cGMP and even better occurrences of erections. Avery important information that men will learn through reading about sildenafil citrate online is that sildenafil will be rendered useless without the introduction of one or more sexual stimuli, since only a sexual stimulus will be the only factor that can initiate the activation of the nitric oxide and cGMP inside a man’s body. Read more…

What's in the news: Mar. 27 -- George Clooney's corrupting influence

"Clooney taught us"
Dr Peter Brindley's critical care medical students at the University of Alberta were consistently doing intubations wrong. It turns out it's the television drama ER's fault, reported Dr Brindley in the journal Resuscitation earlier this month. He watched the fictional MDs doing intubations and, indeed, they did them incorrectly in many instances. But one reader took issue with med students blaming their mistakes on TV: "Holding ER liable for medical students practising incorrect medical procedures is akin to blaming gun violence on video game developers."

Manitoba floods spark water worries
With major flooding set to hit Manitoba, the province's chief medical health officer, Dr Joel Kettner, warned residents that the flooding may contaminate water from wells, and recommended boiling well water before consuming it.

Death by "excited delirium"
Trevor Grimolfson, who died after he was shot with a Taser during an altercation with police in October in Edmonton, died of "excited delirium" and not because he was shot by the Taser, an Alberta medical examiner concluded. "Excited delirium" is not a medically recognized condition or diagnosis. It's a controversial term often used by police departments to "whitewash" the deaths of people in custody, the American Civil Liberties Union has said.

Meanwhile, Quebec has asked police officers to return some of their Taser guns to laboratories for testing after a CBC investigation found that some guns fired higher voltages than they were supposed to.

Rolling the dice
The Calgary Herald speculated that the recession could lead to a rise in the social and health costs of gambling. In related news, a University of Calgary psychology PhD candidate has begun recruiting subjects for a study on the stigma of gambling addiction. [University of Calgary UTODAY]

Where's the weed?
Federal Health Minister Leona Aglukkaq said this week that her department will study potential restrictions on where licensed users of medical marijuana are allowed to smoke.

A coughing fit
A consumer-rights group in Quebec filed an $8-million class-action false advertising lawsuit against the producers of children's cough and cold medicines. The group, Option consommateurs, alleges that eight major drug companies intentionally misled consumers into believing that the drugs would be effective.

Canadians on drugs
A new report on Canadians' prescription drug consumption habits showed that total sales rose nearly 6% in 2008 to $21.4 billion, and that generic drugs now account for more than 50% of that figure. [Canadian Generic Pharmaceutical Association news release] The number of prescriptions filled in 2008 amounts to an average of 14 per Canadian.

"Is there a doctor on board?"
The number of medical emergencies on airplanes is on the rise. A representative of a company that handles emergency calls from airplanes said that the two most common injuries are those caused by the beverage and food carts pushed down the aisles and those caused by bags falling out of the overhead compartments. [Toronto Star] In 2007 I wrote about Canadian doctors' complaints that airlines weren't giving them the resources they needed to help patients in the air.

Too sweet or not sweet enough?
McMaster University researchers were among those who published a study in yesterday's New England Journal of Medicine that showed that -- contrary to what had been assumed -- attempting to bring down the blood sugar levels of patients in intensive care can be more harmful than leaving them at elevated levels. [McMaster Daily News]

K.I.S.S. with hypertension
Simplifying recommendations for family doctors on how to treat patients' hypertension results in better patient outcomes, report University of Western Ontario researchers in the April issue of Hypertension.

"The nature of hypertension management has changed," said Dr Ross Feldman, who led the study. "It’s much more aggressive, and complex, leading to hundreds of recommendations on how to manage high blood pressure... This should be a call to hypertensive patients to go to their family physicians to be prescribed these single pill combinations. It makes both the patients' and doctors' lives easier." [Western News]

More news from across Canada and beyond
Manitoba MP Stephen Fletcher was denied the chance to appeal to the Supreme Court a lower court's decision that the Manitoba public health insurance system was not required to pay him more than its $3,000/month stipend for medical assistance. Mr Fletcher was paralyzed from the neck down when his car hit a moose in 1996.

The Canadian Centre for Policy Alternatives is publishing a blog about the rapidly approaching provincial election in British Columbia. You can read all the healthcare-related articles by clicking .

The Canadian Medical Association has started a series of podcasts on the theme of physician wellness. The first episode, called "The many layers of the healthy
doc," "explores the fine balance between self-awareness, collegiality within the profession and being a healthy physician." [CMA news release]

What's it like to be the White House physician?

Republicans are healthier than Democrats, according to a new study. Why? "The authors hypothesize that the better health reported by Republicans may reflect the Republican value of individual responsibility, which may lead to health-promoting behaviors. They also note that Republicans may exhibit greater religiosity than Democrats, which could lead to greater health-promoting conditions, such as stronger social ties and networks." Maybe.

The US Association of Health Care Journalists announced their 2008 award winners.

More on the Canadian-healthcare-killed-Natasha-Richardson story, this time from a physician writing in the New York Post under the all-capitals headline "CANADACARE MAY HAVE KILLED NATASHA."

What's in the news: Mar. 25 -- Saskatchewan's infant-HIV problem

Saskatchewan's "AIDS crisis"
Nearly one in four HIV-positive infants born in Canada from 2005 to 2007 were born in Saskatchewan, setting off concerns among Saskatchewan public health and obstetrics experts.

Reacting to the news, the Regina Leader-Post wrote, "Saskatchewan has an AIDS crisis."

Dr Moira McKinnon, the province's chief medical officer, is studying the reasons for the disproportionate number of HIV-positive births. She suggested that drug users and sex workers need more attention paid to their health.

How do you solve a problem like obesity?
Obesity, declared Dr Arya Sharma, is not a lifestyle choice. Calling for an expansion of the investment of funding and effort into obesity, Dr Sharma, who's a professor and practitioner in Edmonton and the scientific director of the Canadian Obesity Network, wrote in a Globe and Mail commentary that "too many health professionals also do not understand obesity; they offer advice that is useless, expect the impossible from their patients, fail to acknowledge root causes, or ignore the barriers to treatment."

Quebec's third party regroups
The ADQ party, which lost its official opposition status and its longtime leader, Mario Dumont, in last year's election, is in the process of selecting a new leader. The first person to announce his candidacy is the party's experienced MNA and health critic, Eric Caire, who has for years assailed the Liberal government's health ministers Philippe Couillard and Yves Bolduc on their reluctance to expand privatization options in the healthcare sector.

Come clean
Montreal family physician Marie-Dominique Beaulieu warned that family secrets are detrimental to one's health. Also: did you know the woman Jack Nicholson believed to be his mother turned out to be his sister, and he learned about it from a newspaper article? Bizarre. [ (French only)]

Backseat doctoring
The Natasha-Richardson's-death blame game continues online, at M.D.O.D. (... or -- oops -- maybe not), Pure Pedantry (, for declining immediate medical attention... but really at fault: poor patient education about head trauma), and NHS Blog Doctor (, by which he means defensive medicine and an over-reliance on technology).

Grand Rounds
The weekly collection of health bloggers' best articles was published at a nursing blog this week.