Furosemide 40mg – A Close Look at the Generic Version of Lasix

Lasix is actually the branded version of the generic drug furosemide.  These drugs are mainly diuretic in nature which is also part of their mechanism of action.  Basically, the main purpose of furosemide 40mg is to induce increase in urine in order to get rid of the body’s excess water.  Furosemide 40mg also helps in preventing the absorption of salt so that this compound is passed along the urine.  Furosemide is available in doses of 20mg, furosemide 40mg, and 80mg with furosemide 40mg being the mostly prescribed.

Fluid retention and edema are some of the conditions that furosemide was made to treat.  This is particularly true for people who already suffer from medical conditions like heart diseases, liver diseases, and kidney issues.  Read more…

Future looks bleak for Avandia as safety trial put on hold

Last week saw an rule that there is reason to believe the troubled diabetes drug Avandia (rosiglitazone) does indeed increase cardiovascular risks compared to its direct competitor Actos (pioglitazone).

Now, the FDA appears to be moving to shut down the Canadian-led trial that represented the last chance for maker GlaxoSmithKline to prove its drug is safe. The agency put a "partial clinical hold" on new recruitment for the trial while it updates the lead investigators - Drs Salim Yusef and Hertzel Gerstein of McMaster University - on the results of last week's panel meeting.

While the FDA safety panel stopped short of voting to remove Avandia from the market, the agency can still take action without a vote, and most observers suspect the end is near for Avandia, which has already seen sales collapse in the wake of data suggesting it increases cardiovascular events.

In fact, the same safety concerns were inhibiting recruitment to the TIDE trial. GSK, which agreed in 2007 to fund a head-to-head comparison with pioglitazone, said last week that only 1,100 of an intended 16,000 study participants have volunteered to date.