Get Your Lost Erection Back with Sildenafil Citrate 100mg

Erectile dysfunction (ED) is a sick and naughty male sexual dysfunction to have.  Because of this condition, it inhibits you from having successful intercourse with your female partner.  This is because without an erection, vaginal penetration is not possible.  Fortunately, although only temporary, you can get your erection back using sildenafil citrate 100mg.  Sildenafil citrate 100mg is very effective in providing you the erection you lost due to erectile dysfunction as it is the generic alternative of Viagra, the most popular and highly sought after ED treatment drug.

Sildenafil citrate 100mg is classified as a PDE5 inhibitor drug because it follows the same mechanism of action of drugs belonging to that class.  What PDE5 inhibitor drugs do is that it selectively focuses on the smooth muscles lining the penis.  This smooth muscle relaxes when you are sexually stimulated to allow blood to enter the cavities within the penis so an erection can be achieved.  Once you are no longer sexually aroused, the smooth muscles then contracts back to squeeze the blood out of the penis so the penis becomes limp again.  This is actually what is great about PDE5 inhibitor drugs like sildenafil citrate 100mg because they provide you with a normal-like erection function. Read more…

Relistor may weaken the GI wall

When to beware

As all meds do, mythylnaltrexone bromide (Relistor) has its share of possible side effects, the most common being dizziness, flatulence, mild diarrhea, nausea, stomach pain, vomiting, and hyperhidrosis. Severe reactions include a serious case of any already mentioned, or allergic reactions.

Today, Health Canada and Wyeth Canada added a new possible adverse reaction to the list: a heightened risk of gastrointestinal perforation, especially in those with GI cancers and other conditions that could weaken the gastrointestinal wall.

When Relistor came onto the scene – it was approved by Health Canada on March 28, 2008 – it relieved opioid-induced constipation in palliative-care patients with incurable cancers, end-stage COPD from emphysema, heart failure, Alzheimer’s disease, and so on, when other laxative therapies could not – in under 30 minutes. Administered by subcutaneous injection, it blocks opioids from entering cells, allowing bowels to revert to normal function, while not interfering with the opioid’s ability to relieve pain.

The current warning advises discontinuing Relistor and seeking professional help if severe, persistent symptoms like abdominal pain intensified by movement, nausea and vomiting -- possibly accompanied by fever and chills – worsen, as these can be signs of GI perforation.

It makes one wonder, though, if the original studies on this drug should have lasted a wee bit longer than four months.
Milena Katz