Learn about Erectile Dysfunction and Sildenafil Citrate Online

October 12, 2015

Have you ever wondered how sildenafil acts within your body to help you solve your problems with erectile dysfunction?  Thanks to the instant availability of the Internet and computer devices, you will now be able to learn about ED and sildenafil citrate online right at your fingertips.

If you are curious as to how PDE5 inhibitors such as sildenafil work inside your body, then you can browse on search engines by simply typing in the search box the words sildenafil citrate online.  When you read about the mechanics of the action of sildenafil citrate online, you will learn that it helps protect the enzyme cGMP (short for cyclic guanosine monophosphate) from being degraded by the cGMP-specific PDE5 (short for phosphodiesterase type 5 enzyme) which are evidently located in the penile corpus cavernosum of men.  The free radical NO (short for nitric oxide) found in the penile corpus cavernosum adheres itself to what are called the guanylate cyclase receptors, which then results to the occurrence of elevated amounts of cGMP, thereby leading to the vasodilation or relaxation of the smooth muscles of the inner lining cushions of the helicine arteries (tendril-like arteries of the penis importantly involved in the process of its erection).  Once the smooth muscles relax, it will result to vasodilation and therefore there will be an increased supply of blood flowing into the penile spongy tissue, and the end result would be a successful penile erection.

Additionally, what you would also learn about sildenafil citrate online is that its special molecular makeup is somewhat similar to cGMP (located in the penile corpus cavernosum as well) and functions as an aggressive binding element of PDE5 in the penile corpus cavernosum, which results to more concentrations of cGMP and even better occurrences of erections. Avery important information that men will learn through reading about sildenafil citrate online is that sildenafil will be rendered useless without the introduction of one or more sexual stimuli, since only a sexual stimulus will be the only factor that can initiate the activation of the nitric oxide and cGMP inside a man’s body.

Another important thing to keep in mind when you research about sildenafil citrate online is that when you take sildenafil for your erectile dysfunction, it is advisable that you must not take it with a high-fat meal because the absorption and effectiveness will be reduced.  Past studies have revealed that taking sildenafil with a high-fat meal will lead to a waiting time of more than an hour or two before it takes effect, and the overall potency will also be reduced by almost up to one-third.

In case you are fed up with buying sildenafil at your local pharmacy because of the hefty prices, you can buy some sildenafil citrate online without spending a lot of your money.  Many online pharmacies, if you are patient enough to look around, offer nice discounts and other perks if you buy sildenafil citrate online from them.

If you have never bought any medicines online yet, then it is a good practice for you to try buying some sildenafil citrate online.  You will definitely enjoy the benefits of buying sildenafil citrate online and at the same time solve your erectile dysfunction issues once and for all.