Learn about Erectile Dysfunction and Sildenafil Citrate Online

Have you ever wondered how sildenafil acts within your body to help you solve your problems with erectile dysfunction?  Thanks to the instant availability of the Internet and computer devices, you will now be able to learn about ED and sildenafil citrate online right at your fingertips.

If you are curious as to how PDE5 inhibitors such as sildenafil work inside your body, then you can browse on search engines by simply typing in the search box the words sildenafil citrate online.  When you read about the mechanics of the action of sildenafil citrate online, you will learn that it helps protect the enzyme cGMP (short for cyclic guanosine monophosphate) from being degraded by the cGMP-specific PDE5 (short for phosphodiesterase type 5 enzyme) which are evidently located in the penile corpus cavernosum of men.  The free radical NO (short for nitric oxide) found in the penile corpus cavernosum adheres itself to what are called the guanylate cyclase receptors, which then results to the occurrence of elevated amounts of cGMP, thereby leading to the vasodilation or relaxation of the smooth muscles of the inner lining cushions of the helicine arteries (tendril-like arteries of the penis importantly involved in the process of its erection).  Once the smooth muscles relax, it will result to vasodilation and therefore there will be an increased supply of blood flowing into the penile spongy tissue, and the end result would be a successful penile erection.

Additionally, what you would also learn about sildenafil citrate online is that its special molecular makeup is somewhat similar to cGMP (located in the penile corpus cavernosum as well) and functions as an aggressive binding element of PDE5 in the penile corpus cavernosum, which results to more concentrations of cGMP and even better occurrences of erections. Avery important information that men will learn through reading about sildenafil citrate online is that sildenafil will be rendered useless without the introduction of one or more sexual stimuli, since only a sexual stimulus will be the only factor that can initiate the activation of the nitric oxide and cGMP inside a man’s body. Read more…

iPad: Elegant. Fun. Seductive. Frustrating. Coming to Canada April 23

I've tested the new iPad and found it irresistible.The touch screen is marvellous to use. Smooth as butter (wipe after using), intuitive as your fingers, clear bright images. Fast, very fast.

Out of the box, there's not much to it -- looks like a big iTouch. There's a USB cord to plug it into a computer and that's it. Once you'd done that and downloaded the most recent version of iTunes, you're good to go.

The first impression is that it really is just a big, version of the iTouch -- with a book store. This is clearly Apple's challenge to e-books, Kindle, Sony, the Nook and all those yet to come. To get you started, there's a free copy of Winnie-the-Pooh which looks just about as good sitting on it's virtual wooden book shelf as it did when you were six years old and were given a fresh copy by your Grannie. Take it down an give it a flip thru, you won't be disappointed. The coloured pictures are lush, the type crystal clear.

The iTunes store offers a stack of new apps for the iPad from the games to the Wall Street Journal. The latter opens instantly and gives you a pared down version of the paper, like the NYTimes, it's free. There's music and movies to sample, buy or rent, e-mail, a calendar, contacts, notes, maps and YouTube.

Using the device for work is not quite as easy. You'll want to buy the wireless keybaord for starters. Then, you have to download iWork which consists of a word processor, a spreadsheet and presentation software. Each cost $9.99 US. You can e-mail your creations or upload them to the iWork website and then invite others to see them there if you and they wish. It's finicky and ties you firmly to Apple as Mr Jobs intends.

What it can't do or doesn't have: a camera, a phone, a usb connection for anything but itunes, flash video, multi-tasking, copying between programs, say, word processor to Safari, which, incidentally, is the only browser iPad uses.

What it does have: battery life of 10+ hours; the ability to mesmerize. iPad makes you wish you could use it for all your computing needs -- you can't.